New strategy by which HCV evades host immune defences
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Bordetella evades the host immune system by inducing IL-10 through a type III effector, BopN
The inflammatory response is one of several host alert mechanisms that recruit neutrophils from the circulation to the area of infection. We demonstrate that Bordetella, a bacterial pathogen, exploits an antiinflammatory cytokine, interleukin-10 (IL-10), to evade the host immune system. We identified a Bordetella effector, BopN, that is translocated into the host cell via the type III secretion...
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ژورنال
عنوان ژورنال: Nature Reviews Gastroenterology & Hepatology
سال: 2013
ISSN: 1759-5045,1759-5053
DOI: 10.1038/nrgastro.2013.127